Police say around 10.30pm, a 56-year-old man was being transported by the ambulance crew at Gregory Street, when he punched the male paramedic in the face before throwing an item at the female paramedic driving the ambulance.
Both paramedics urgently withdrew from the escalating violence and alerted police.
Police say the male patient then drove away in the ambulance.
“The Queensland Ambulance Service does not tolerate aggressive behaviour or physical violence” QAS said in a post shared on Facebook.
Police located the stolen ambulance and the patient a short distance away on Hull Street before taking the man into custody.
Both paramedics suffered non-life threatening injuries.
The man is assisting police with their inquiries and investigations are ongoing.